Just outside London, sheltered by huge concrete walls sits Moorcroft Asylum. The Asylum has been abandoned since the 60's, but only by Mortals. Now Moorcroft is a hot-spot for Supernatural activity, the main building is used by Changelings so they may practice their rituals away from mortal eyes. Vampires guard their dirty secrets beneath the East Building far from the light of day. Werewolves stalk the grounds hunting evil spirits that pass through here, grateful of a place where they can be safe from the Pure. The Ghosts of those who died at Moorcroft walk the ground lamenting their passing until they find a Sin-Eater to help them pass on. Who knows what other supernatural stalk the grounds of Moorcroft.
Now mortals return to the Asylum, some hapless group of teenagers on a dare and a team of Hunters hellbent of ridding Moorcroft of the dark menace within its walls.
Now each person, Kindred, Lost, Forsaken or whatever else must fight for survival against those who now threaten what they do.