I think some "hard" drugs should be reconsidered. LSD, psilocybin mushrooms, DMT, and ecstasy, especially ecstasy should be regulated. So many people end up in bad situations when they get their hands on tainted ecstasy, which may not even be ecstasy. All of the above psychedelics are mostly harmless in comparison to alcohol but bad things happen because you're getting them from criminals, on the other hand, regulated and marketed mushrooms, LSD and DMT would see massive increase in use among the population, because that stuff is rare. Not to mention there is some medical promise in first three, they all need extensive research still, but i've been reading about psychiatrist using LSD and mushrooms to incite breakthroughs with their patients.